Role of ubiquitination in the regulation of plant defence against pathogens

被引:148
作者
Devoto, A
Muskett, PR
Shirasu, K
机构
[1] John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England
[2] Max Planck Inst Plant Breeding Res, Dept Plant Microbe Interact, D-50829 Cologne, Germany
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1016/S1369-5266(03)00060-8
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Ubiquitination is emerging as a common regulatory mechanism that controls a range of cellular processes in plants. Recent exciting discoveries from several laboratories suggest that ubiquitination may also play an important role in plant disease resistance. Several putative ubiquitin ligases have been identified as defence regulators. In addition, a combination of genetic screens and gene-silencing technologies has identified subunits and proposed regulators of SCIF ubiquitin ligases as essential components of resistance (R)-gene-mediated resistance. Although no ubiquitin ligase targets that are associated with disease resistance have yet been identified in plants, there is evidence that this well-known protein-modification system may regulate plant defences against pathogens.
引用
收藏
页码:307 / 311
页数:5
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