Observational cohort studies: lessons learnt from the University of Toronto Psoriatic Arthritis Program

被引：108

作者：

Gladman, Dafna D. ^{[1
]}

Chandran, Vinod ^{[1
]}

机构：

[1] Toronto Western Hosp, Psoriat Arthrit Program, Ctr Prognosis Studies Rheumat Dis, Toronto, ON M5T 2S8, Canada

来源：

RHEUMATOLOGY | 2011年 / 50卷 / 01期

基金：

加拿大健康研究院;

关键词：

Psoriatic arthritis; Psoriasis; Spondyloarthritis; International collaboration; Gene; Phenotype; Prognosis; Longitudinal observational cohort; Prospective studies; RELATIVE RISK MODEL; CLINICAL INDICATORS; DISEASE; HLA; PROGRESSION; ASSOCIATION; THERAPY; HEALTH; QUESTIONNAIRE; METHOTREXATE;

D O I：

10.1093/rheumatology/keq262

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Observational cohorts have emerged as important resources to study course and prognosis of chronic disease, and also facilitate phenotype definition for genetic studies. We describe the development and accomplishments of the PsA cohort at the University of Toronto as an example of an observational cohort that has allowed the description of disease manifestations, course and prognosis of PsA. We also describe the development of an international collaboration based on this cohort, which will further be used to study the incidence, prevalence and predictive factors for the development of PsA among patients with psoriasis.

引用

页码：25 / 31

页数：7

共 56 条

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