The clinical expression of allergy in the skin

被引：11

作者：

Ring, J ^{[1
]}

Thewes, M ^{[1
]}

机构：

[1] Tech Univ Munich, Dept Dermatol & Allergy Biederstein, Div Environm Dermatol & Allergy GSF, D-80802 Munich, Germany

来源：

ALLERGY | 1999年 / 54卷 / 03期

关键词：

D O I：

10.1111/j.1398-9995.1999.0_083.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The cutaneous immune system has evolved to protect the organism from potential exogenous pathogens in a complex manner. Recent investigations of the special role of the skin in allergy have focused on the proinflammatory potential of various cells such as Langerhans' cells, keratinocytes, mast cells (MC), endothelial cells, and dermal fibroblasts. Furthermore, in processing and reacting to antigens, infiltrating inflammatory cells (lymphocytes; monocytes; macrophagesi and eosinophil, neutrophil, and basophil granulocytes) play an important role both by cell-cell interactions with specific receptors on cell surfaces and via soluble mediators.

引用

页码：192 / 197

页数：6

共 38 条

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