The pyridinium reduction route to alkaloids:: a synthesis of (±)-tashiromine

被引：42

作者：

Bates, RW

Boonsombat, J

机构：

[1] Chulabhorn Res Inst, Bangkok 10210, Thailand

[2] Chulalongkorn Univ, Dept Chem, Bangkok 10330, Thailand

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 07期

关键词：

D O I：

10.1039/b100407g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An indolizidine natural product, (+/-)-tashiromine, has been synthesized as a single diastereoisomer by a simple protocol. The key steps of the synthesis include a heterogeneous Sonogashira reaction and a stereoelectronically controlled reduction of a bicyclic pyridinium ion.

引用

页码：654 / 656

页数：3

共 24 条

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