The End and After: How Dying Cells Impact the Living Organism

被引:31
作者
Green, Douglas R. [1 ]
机构
[1] St Jude Childrens Hosp, Dept Immunol, Memphis, TN 38105 USA
关键词
AUTOPHAGY; APOPTOSIS; DEATH;
D O I
10.1016/j.immuni.2011.10.003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
All cells die, but the manner of death dictates interactions with living cells and consequences for the organism, especially with respect to the immune response. Here we discuss the different modes of cell death as they relate to this rapidly evolving field.
引用
收藏
页码:441 / 444
页数:4
相关论文
共 12 条
[1]   Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor [J].
Coppe, Jean-Philippe ;
Patil, Christopher K. ;
Rodier, Francis ;
Sun, Yu ;
Munoz, Denise P. ;
Goldstein, Joshua ;
Nelson, Peter S. ;
Desprez, Pierre-Yves ;
Campisi, Judith .
PLOS BIOLOGY, 2008, 6 (12) :2853-2868
[2]   Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival [J].
Elgendy, Mohamed ;
Sheridan, Clare ;
Brumatti, Gabriela ;
Martin, Seamus J. .
MOLECULAR CELL, 2011, 42 (01) :23-35
[3]   Apoptosis-induced compensatory proliferation. The Cell is dead. Long live the Cell! [J].
Fan, Yun ;
Bergmann, Andreas .
TRENDS IN CELL BIOLOGY, 2008, 18 (10) :467-473
[4]  
Green D.R., 2011, Means to an End: Apoptosis and Other CelDeath Mechanisms
[5]   RIPK-Dependent Necrosis and Its Regulation by Caspases: A Mystery in Five Acts [J].
Green, Douglas R. ;
Oberst, Andrew ;
Dillon, Christopher P. ;
Weinlich, Ricardo ;
Salvesen, Guy S. .
MOLECULAR CELL, 2011, 44 (01) :9-16
[6]   Recent progress in elucidating the molecular mechanism of the mitochondrial permeability transition pore [J].
Leung, Anna W. C. ;
Halestrap, Andrew P. .
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2008, 1777 (7-8) :946-952
[7]   Autophagy in immunity and inflammation [J].
Levine, Beth ;
Mizushima, Noboru ;
Virgin, Herbert W. .
NATURE, 2011, 469 (7330) :323-335
[8]   Apoptotic Cells Activate the "Phoenix Rising" Pathway to Promote Wound Healing and Tissue Regeneration [J].
Li, Fang ;
Huang, Qian ;
Chen, Jiang ;
Peng, Yuanlin ;
Roop, Dennis R. ;
Bedford, Joel S. ;
Li, Chuan-Yuan .
SCIENCE SIGNALING, 2010, 3 (110) :ra13
[9]   Self-eating and self-killing: crosstalk between autophagy and apoptosis [J].
Maiuri, M. Chiara ;
Zalckvar, Einat ;
Kimchi, Adi ;
Kroemer, Guido .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (09) :741-752
[10]   Distinct death mechanisms in Drosophila development [J].
Ryoo, Hyung Don ;
Baehrecke, Eric H. .
CURRENT OPINION IN CELL BIOLOGY, 2010, 22 (06) :889-895