High dose fibrinogen administration for acute therapy of coagulopathy during massive perioperative transfusion

被引：34

作者：

Heindl, B

DeLorenzo, C

Spannagl, M

机构：

[1] Univ Munich, Anasthesiol Klin, D-80336 Munich, Germany

[2] Univ Munich, Abt Hamostaseol & Transfusionsmed, Munich, Germany

来源：

ANAESTHESIST | 2005年 / 54卷 / 08期

关键词：

coagulopathy; fibrinogen; fibrin polymerization; hemodilution; thrombelastography;

D O I：

10.1007/s00101-005-0865-7

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

During acute and severe perioperative bleeding a coagulopathy due to depletion, consumption and dilution of clotting factors and thrombocytes may occur. Diagnosis and therapy of such a coagulopathy should take place immediately. We report two cases of acute coagulopathy during perioperative bleeding and massive transfusion, which were treated successfully by administration of high dose fibrinogen concentrate. Diagnosis and treatment control were performed by thrombelastography.

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收藏

页码：787 / 790

页数：4

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