Systematic investigation of preparing biocompatible, single, and small ZnS-capped CdSe quantum dots with amphiphilic polymers

被引：126

作者：

Anderson, Robin E. ^{[1
]}

Chan, Warren C. W. ^{[1
,2
]}

机构：

[1] Univ Toronto, Inst Biomat & Biomed Engn, Ctr Biomat & Biomol Res, Toronto, ON, Canada

[2] Univ Toronto, Dept Mat Sci & Engn, Toronto, ON, Canada

来源：

ACS NANO | 2008年 / 2卷 / 07期

关键词：

quantum dots; semiconductor nanciparticles; amphiphilic polymer; polymer wrapping; protein adsorption;

D O I：

10.1021/nn700450g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The successful transfer of nanoparticles between solvents is critical for many applications. We evaluated the impact of amphiphilic polymer composition on the size, transfer efficiency, and biocompatibility of tri-n-octylphosphine oxide/hexadecylamine-stabilized semiconductor ZnS-capped CdSe and CdS-capped CdTexSe1-x quantum dots (QDs). We also investigated the adsorption of various proteins onto the surface of these QDs and studied the effect of surface chemistry on non-specific protein binding. The results from these studies will have implications in the design of QDs and other nanoparticles for biological and biomedical applications.

引用

页码：1341 / 1352

页数：12

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