Hepatoprotective effects of emodin from Ventilago leiocarpa

被引：117

作者：

Lin, CC

Chang, CH

Yang, JJ

Namba, T

Hattori, M

机构：

[1] CHIA NAN JR COLL PHARM,DEPT PHARM,TAINAN,TAIWAN

[2] TOYAMA MED & PHARMACEUT UNIV,RES INST WAKAN YAKU,TOYAMA,JAPAN

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1996年 / 52卷 / 02期

关键词：

Ventilgo leiocarpa; Rhamnaceae; emodin; hepatoprotection; carbon tetrachloride (CCl4); D-galactosamine (D-GalN);

D O I：

10.1016/0378-8741(96)01397-9

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A major component of ethyl acetate (EtOAc) and chloroform (CHCl3) fractions of Ventilago leiocarpa Bunge (Rhamnaceae), emodin, was isolated and exhibited hepatoprotective effects on carbon tetrachloride (CCl4) as well as D-galactosamine (D-GalN)-induced liver damage. The histopathological examination also clearly showed that emodin reduced lymphocyte cells, Kupffer cells, ballooning degeneration, cell necrosis and hyaline degeneration on CCl4 and D-galactosamine-induced tests.

引用

页码：107 / 111

页数：5

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