RNA splicing: What has phosphorylation got to do with it?

被引：95

作者：

Misteli, T ^{[1
]}

机构：

[1] NCI, NIH, Bethesda, MD 20892 USA

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 06期

关键词：

D O I：

10.1016/S0960-9822(99)80128-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Many pre-mRNA splicing factors are phosphorylated in vivo, but the role of this modification has been unclear. Recent observations suggest that phosphorylation modulates protein-protein interactions within the spliceosome, thereby contributing to dynamic structural reorganization of the spliceosome during splicing.

引用

页码：R198 / +

页数：4

共 12 条

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