Intra-individual variation in creatinine and cystatin C

被引：32

作者：

Bandaranayake, Niluka ^{[1
]}

Ankrah-Tetteh, Thelma ^{[1
]}

Wijeratne, Sethsiri ^{[1
]}

Swaminathan, Ramasamyiyer ^{[1
]}

机构：

[1] St Thomas Hosp, Dept Chem Pathol, London SE1 7EH, England

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2007年 / 45卷 / 09期

关键词：

creatinine; cystatin C; glomerular filtration rate; intra-individual variation;

D O I：

10.1515/CCLM.2007.256

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 [基础医学];

摘要：

Background: Serum creatinine and cystatin C are measured in the assessment of glomerular filtration rate. Biological variation of an analyte is an important determinant of its usefulness. Intra-individual variation in serum creatinine and cystatin C in healthy subjects was determined in this study. Methods: Weekly blood samples were taken from 10 healthy subjects and analysed for creatinine (kinetic Jaffe method) and for cystatin C (by nephelometry). Results: Intra-individual variations for serum creatinine and cystatin C were 6.1% and 4.55%, respectively. Index of individuality values were similar for the analytes (0.35 for both). Conclusion: Intra-individual variations for serum creatinine and cystatin C were similar in healthy subjects.

引用

页码：1237 / 1239

页数：3

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