Prolonged longevity of hypopituitary dwarf mice

被引：99

作者：

Bartke, A ^{[1
]}

Brown-Borg, H

Mattison, J

Kinney, B

Hauck, S

Wright, C

机构：

[1] So Illinois Univ, Sch Med, Dept Physiol, Carbondale, IL 62901 USA

[2] Univ N Dakota, Sch Med, Dept Physiol, Edwin James Res Ctr, Grand Forks, ND 58202 USA

[3] NIA, NIH, Anim Ctr, Poolesville, MD 20837 USA

来源：

EXPERIMENTAL GERONTOLOGY | 2001年 / 36卷 / 01期

关键词：

D O I：

10.1016/S0531-5565(00)00205-9

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

In two types of mutant dwarf mice, congenital deficiencies in pituitary function are associated with remarkably increased life expectancy. In this review, we will describe the key phenotypic characteristics of these animals, the evidence that they exhibit delayed aging, and the mechanisms that are suspected to account for their prolonged longevity. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

页码：21 / 28

页数：8

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