Exacerbations in cystic fibrosis:: 2 • Prevention

被引：33

作者：

Bell, Scott C.

Robinson, Philip J.

机构：

[1] Prince Charles Hosp, Adult Cyst Fibrosis Ctr, Brisbane, Qld 4032, Australia

[2] Univ Queensland, Sch Med, St Lucia, Qld 4067, Australia

[3] Royal Childrens Hosp, Dept Resp Med, Melbourne, Vic, Australia

来源：

THORAX | 2007年 / 62卷 / 08期

关键词：

D O I：

10.1136/thx.2006.060897

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

The life span of people with cystic fibrosis (CF) has increased dramatically over the past 50 years. Many factors have contributed to this improvement. Respiratory exacerbations of CF lung disease are associated with the need for hospitalisation and antibiotic treatment, reduction in the quality of life, fragmented sleep and mortality. A number of preventive treatment strategies have been developed to reduce the frequency and severity of respiratory exacerbations in CF including mucolytic agents, physiotherapy and exercise, antibiotics, nutritional strategies, anti-inflammatory treatments and vaccinations against common respiratory pathogens. The evidence for each of these treatments and their potential impact is discussed.

引用

页码：723 / 732

页数：10

共 126 条

[1] Combination antibiotic susceptibility testing to treat exacerbations of cystic fibrosis associated with multiresistant bacteria: a randomised, double-blind, controlled clinical trial [J].