Influence of acute resistance exercise on cardiac biomarkers in untrained women

This study was conducted to determine if an initial bout of resistance (weight lifting) exercise by untrained women results in any alterations in indicators of acute myocardial infarction (AMI). Untrained women performed 4 resistance exercises at 70% of their 1 repetition maximum. Blood samples were obtained during the 12 h post-exercise and analyzed for total creatine kinase (CK)-MB, CK-MB subforms 1 and 2, and the relative lymphocyte percentage. Exercise resulted in significant increases in total CK-MB, CK-MB1, CK-MB2, and the CK-MB2/CK-MB1 ratio, total leukocyte count, and lymphocyte count. Using several criteria for the assessment of AMI, 22-25% of subjects completing the protocol demonstrated increases in CK-MB2, CK-MB2/CK-MB1 ratio, and relative lymphocyte percentages that were suggestive of AMI. Thus, our data suggest that moderate resistance exercise can significantly alter blood indicators of AMI, emphasizing the need to determine recent exercise history in patients with possible AMI. (C) 2003 Elsevier Inc.