Mechanisms of disease: Leukotrienes

被引:877
作者
Peters-Golden, Marc
Henderson, William R., Jr.
机构
[1] Univ Michigan Hlth Syst, Dept Internal Med, Div Pulm & Crit Care Med, Ann Arbor, MI 48109 USA
[2] Univ Washington, Dept Med, Div Allergy & Infect Dis, Ctr Allergy & Inflammat, Seattle, WA USA
关键词
D O I
10.1056/NEJMra071371
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review of leukotrienes, which are lipid mediators with a broad array of clinical effects, and leukotriene receptors considers the biochemical and physiological aspects of these molecules, examines their roles in asthma and other diseases, and explains the pharmacologic effects of antileukotriene agents. Copyright © 2007 Massachusetts Medical Society.
引用
收藏
页码:1841 / 1854
页数:14
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