Chemometric analysis of complex hyphenated data - Improvements of the component detection algorithm

被引：19

作者：

Windig, W.

Smith, W. F.

机构：

[1] Eigenvector Res Inst, Wenatchee, WA 98801 USA

[2] Eastman Kodak Co, Rochester, NY 14650 USA

来源：

JOURNAL OF CHROMATOGRAPHY A | 2007年 / 1158卷 / 1-2期

关键词：

chemometrics; CODA; liquid chromatography/mass spectrometry; baseline correction;

D O I：

10.1016/j.chroma.2007.03.081

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Component detection algorithm (CODA) is a method to quickly extract the high-quality mass chromatograms from complex liquid chromatography/electrospray ionization mass spectrometry (LC/MS) data sets, saving operators hours of analysis time. It appeared, however, that mass chromatograms with a limited baseline problem were ignored. This paper describes several methods to increase the tolerance for mass chromatograms with a baseline. (c) 2007 Elsevier B.V. All rights reserved.

引用

收藏

页码：251 / 257

页数：7

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