Magnetic resonance imaging of the thalamus in first-episode psychosis

被引：68

作者：

Ettinger, U ^{[1
]}

Chitnis, XA ^{[1
]}

Kumari, V ^{[1
]}

Fannon, DC ^{[1
]}

Sumich, AL ^{[1
]}

O'Ceallaigh, S ^{[1
]}

Doku, VC ^{[1
]}

Sharma, T ^{[1
]}

机构：

[1] Univ London, Dept Psychiat, Sect Cognit Psychopharmacol, Inst Psychiat,Div Psychol Med, London SE5 8AF, England

来源：

AMERICAN JOURNAL OF PSYCHIATRY | 2001年 / 158卷 / 01期

关键词：

D O I：

10.1176/appi.ajp.158.1.116

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: There is some evidence of thalamic abnormalities in schizophrenia. This study investigated thalamic volumes in patients experiencing their first episode of psychosis and nonpsychotic comparison subjects. Method: Magnetic resonance imaging scans were obtained for 38 patients and 29 comparison subjects. Patients' symptoms were rated by research psychiatrists using the Positive and Negative Syndrome Scale. Results: Thalamic volumes were smaller in patients than in comparison subjects. There were no significant correlations between thalamic volumes and symptom scores. Conclusions: Thalamic abnormalities are present close to the onset of psychosis.

引用

页码：116 / 118

页数：3

共 19 条

[1] THALAMIC ABNORMALITIES IN SCHIZOPHRENIA VISUALIZED THROUGH MAGNETIC-RESONANCE IMAGE AVERAGING [J].