Human rhinovirus 3C protease inhibitors: recent developments

被引：7

作者：

Wang, QM ^{[1
]}

机构：

[1] Eli Lilly & Co, Lilly Res Labs, Infect Dis Res, Indianapolis, IN 46285 USA

来源：

EXPERT OPINION ON THERAPEUTIC PATENTS | 1998年 / 8卷 / 09期

关键词：

human rhinovirus; rhinovirus 3C protease; viral protease inhibitors;

D O I：

10.1517/13543776.8.9.1151

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

As members of the picomavirus family, human rhinoviruses (HRVs) are the major cause of the common cold in humans. In recent years, considerable efforts have been made in the development of anti-HRV compounds targeting rhinovirus enzymes including the viral proteases essential for viral replication. This article summarises the most recent approaches in designing novel HRV 3C protease inhibitors for the treatment of rhinovirus infections.

引用

页码：1151 / 1156

页数：6

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