α-fluorination of β-dicarbonyl compounds using p-iodotoluene difluoride under neutral conditions

被引：32

作者：

Yoshida, M ^{[1
]}

Fujikawa, K ^{[1
]}

Sato, S ^{[1
]}

Hara, S ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Engn, Div Mol Chem, Sapporo, Hokkaido 0608628, Japan

来源：

ARKIVOC | 2003年

关键词：

fluorination; p-iodotoluene difluoride; beta-dicarbonyl compounds;

D O I：

10.3998/ark.5550190.0004.605

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A selective introduction of a fluorine atom into the alpha-position of beta-dicarbonyl compounds was achieved using p-iodotoluene difluoride. The reaction proceeded under mild conditions and monofluorination of beta-ketoesters, ketoamides, and diketones selectively took place.

引用

页码：36 / 42

页数：7

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