α-Functionalization of Carbonyl Compounds Using Hypervalent Iodine Reagents

被引：223

作者：

Merritt, Eleanor A. ^{[1
]}

Olofsson, Berit ^{[1
]}

机构：

[1] Stockholm Univ, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden

来源：

SYNTHESIS-STUTTGART | 2011年 / 04期

基金：

瑞典研究理事会;

关键词：

catalysis; asymmetric synthesis; oxidation; hypervalent iodine; C-C bond formation; M-CHLOROPERBENZOIC ACID; P-IODOTOLUENE DIFLUORIDE; ONE-POT SYNTHESIS; PHENYLIODINE(III) BIS(TRIFLUOROACETATE) PIFA; NUCLEOPHILIC VINYLIC SUBSTITUTIONS; IN-SITU GENERATION; BETA-KETO SULFONES; SILYL ENOL ETHERS; DIARYLIODONIUM SALTS; EFFICIENT METHOD;

D O I：

10.1055/s-0030-1258328

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Functionalized carbonyl compounds are versatile intermediates in organic synthesis. A broad range of both carbon and heteroatom substituents can be introduced into the alpha-position of carbonyl compounds using hypervalent iodine reagents. Herein we summarize the use of these environmentally benign reagents with particular emphasis on catalytic and asymmetric methodology developed over the past decade.

引用

页码：517 / 538

页数：22

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