Membrane biology:: Membrane-regulated transcription

被引:25
作者
Vik, Å [1 ]
Rine, J [1 ]
机构
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
关键词
D O I
10.1016/S0960-9822(00)00822-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The activation of membrane-bound transcription factors involves release from the membrane by proteolysis. Recent studies show that, for some proteins, cleavage is performed by the proteasome, whereas others require specific proteases.
引用
收藏
页码:R869 / R871
页数:3
相关论文
共 17 条
[1]   A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood [J].
Brown, MS ;
Goldstein, JL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (20) :11041-11048
[2]   The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane [J].
Cox, JS ;
Chapman, RE ;
Walter, P .
MOLECULAR BIOLOGY OF THE CELL, 1997, 8 (09) :1805-1814
[3]   Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain [J].
Gu, W ;
Roeder, RG .
CELL, 1997, 90 (04) :595-606
[4]   The ubiquitin system [J].
Hershko, A ;
Ciechanover, A .
ANNUAL REVIEW OF BIOCHEMISTRY, 1998, 67 :425-479
[5]  
Hoppe T, 2000, CELL, V102, P577, DOI 10.1016/S0092-8674(00)00080-5
[6]   Signaling and subcellular targeting by membrane-binding domains [J].
Hurley, JH ;
Misra, S .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2000, 29 :49-79
[7]   MULTIPLE PROTEOLYTIC SYSTEMS, INCLUDING THE PROTEASOME, CONTRIBUTE TO CFTR PROCESSING [J].
JENSEN, TJ ;
LOO, MA ;
PIND, S ;
WILLIAMS, DB ;
GOLDBERG, AL ;
RIORDAN, JR .
CELL, 1995, 83 (01) :129-135
[8]   Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb [J].
Jiang, J ;
Struhl, G .
NATURE, 1998, 391 (6666) :493-496
[10]   PHOSPHORYLATION OF THE TRANSCRIPTION FACTOR-PHO4 BY A CYCLIN-CDK COMPLEX, PHO80-PHO85 [J].
KAFFMAN, A ;
HERSKOWITZ, I ;
TJIAN, R ;
OSHEA, EK .
SCIENCE, 1994, 263 (5150) :1153-1156