The predictive value of CSF oligoclonal banding for MS 5 years after optic neuritis

被引：62

作者：

Cole, SR

Beck, RW

Moke, PS

Kaufman, DI

Tourtellotte, WW

机构：

[1] Jaeb Ctr Hlth Res Inc, Tampa, FL 33613 USA

[2] Michigan State Univ, Ctr Clin, Ctr Clin Neurosci, E Lansing, MI 48824 USA

[3] Vet Adm Wadsworth Med Ctr, Los Angeles, CA 90073 USA

来源：

NEUROLOGY | 1998年 / 51卷 / 03期

关键词：

D O I：

10.1212/WNL.51.3.885

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The predictive value of CSF oligoclonal banding for the development of clinically definite MS (CDMS) within 5 years after optic neuritis was assessed in 76 patients enrolled in the Optic Neuritis Treatment Trial. The presence of oligoclonal bands was associated with the development of CDMS (p = 0.02). However, the results suggest that CSF analysis is only useful in the risk assessment of optic neuritis patients when brain MRI is normal and is not of predictive value when brain MRI lesions are present at the time of optic neuritis.

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页码：885 / 887

页数：3

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