Potential roles of heterotrimeric G proteins of the endomembrane system

被引：49

作者：

Nurnberg, B ^{[1
]}

AhnertHilger, G ^{[1
]}

机构：

[1] HUMBOLDT UNIV BERLIN, INST ANAT, BERLIN, GERMANY

来源：

FEBS LETTERS | 1996年 / 389卷 / 01期

关键词：

effector; G protein; receptor; signal transduction; vesicle function;

D O I：

10.1016/0014-5793(96)00584-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Heterotrimeric G proteins are recognized as versatile switches linking cell surface receptors to cellular effecters. Beside their location at the plasma membrane G proteins are found on intracellular membranes. Studies with modulators of G protein activity suggest that G proteins associated with organelle membranes are involved in various steps of secretion and vesicular function. In contrast to hormonal responses involving G proteins little is currently known about possible receptors or activators and effecters interacting with intracellular G proteins. This short review focuses on recent developments elucidating the role of organelle-associated G proteins.

引用

页码：61 / 65

页数：5

共 68 条

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