Sepsis associated encephalopathy (SAE): A review

被引：38

作者：

Green, R ^{[1
]}

Scott, LK ^{[1
]}

Minagar, A ^{[1
]}

Conrad, S ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Dept Neurol & Med, Shreveport, LA 71130 USA

来源：

FRONTIERS IN BIOSCIENCE-LANDMARK | 2004年 / 9卷

关键词：

sepsis; encephalopathy; shock; septic shock; altered mental status; review;

D O I：

10.2741/1250

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Sepsis associated encephalopathy (SAE) is a poorly understood condition that is associated with severe sepsis and appears to have a negative influence on survival. The incidence of encephalopathy secondary to sepsis is unknown. Amino acid derangements, blood-brain barrier disruption, abnormal neurotransmitters, and direct CNS effect are possible causes of septic encephalopathy. Research has not defined the pathogenesis of SAE.

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页码：1637 / 1641

页数：5

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