Susceptibilities to amphotericin B and fluconazole of Candida species in TSARY 2002

被引：40

作者：

Yang, YL

Li, SY

Cheng, HH

Lo, HJ ^{[1
]}

机构：

[1] Natl Hlth Res Inst, Div Clin Res, Miaoli County 350, Taiwan

[2] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu 300, Taiwan

[3] Ctr Dis Control, Div Lab Res & Dev, Lab Mycopathogen Chlamydia & Mycoplasma, Taipei 11561, Taiwan

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2005年 / 51卷 / 03期

关键词：

Candida; susceptibility; resistance;

D O I：

10.1016/j.diagmicrobio.2004.11.004

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Susceptibilities to amphotericin B and fluconazole of 909 Candida species collected during the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) in 2002 were determined by the broth microdilution method. There were 395 (43.5%) Candida albicans, 244 (26.8%) C. tropicalis, 187 (20.6%) C. glabrata, 63 (6.9%) C. parapsilosis, 9 (1%) C. krusei, and 11 (1.2%) others. Among them, 23 (2.5%) isolates were resistant to amphotericin B. They consisted of 10 C. glabrata, 6 C. krusei, 3 C. albicans, 1 C. tropicalis, 1 C. parapsilosis, and 2 others. The resistance rate to amphotericin B has increased compared with that of TSARY 1999 (2.5% versus 0.5%). There were 7 C. krusei, 5 C. albicans, 3 C. glabrata, and 2 others isolates resistant to fluconazole. The resistance rate to fluconazole has decreased from 8.4% in 1999 to 1.9% in 2002. A pattern of coresistance to both amphotericin B and fluconazole was observed. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：179 / 183

页数：5

共 21 条

[1] The epidemiology of hematogenous candidiasis caused by different Candida species [J].