The 1993 dengue 2 epidemic in Charters Towers, North Queensland: clinical features and public health impact

被引:30
作者
McBride, WJH [1 ]
Mullner, H [1 ]
LaBrooy, JT [1 ]
Wronski, I [1 ]
机构
[1] James Cook Univ N Queensland, Sch Publ Hlth & Trop Med, Townsville, Qld 4811, Australia
关键词
D O I
10.1017/S0950268898001058
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In 1993 an epidemic caused by dengue virus type 2 occurred in several North Queensland population centres. Charters Towers, estimated population 10000, had 155 officially notified cases. An analysis of symptoms was undertaken using a random sample of 1000 residents to determine specificity of symptoms, the subclinical infection rate, and to establish the true extent of the epidemic. Retrospective diagnoses of dengue fever were based on the presence of both serum dengue 2 neutralizing antibody and presence of symptoms. An estimated 20 % of the population had dengue fever. The rate of subclinical infections in this epidemic was 14.6 %. There were no symptoms that were specific for dengue fever. Bleeding occurred more frequently in people who recalled a previous dengue infection during a dengue 1 epidemic 12 years earlier (55.6 % vs. 16.8 %, P = 0.003). Surveillance for future epidemics should be based on serological and virological confirmation of dengue virus infection amongst symptomatic patient.
引用
收藏
页码:151 / 156
页数:6
相关论文
共 22 条
[1]  
[Anonymous], 1994, SCI PUBL PAN AM HLTH
[2]   A PROSPECTIVE-STUDY OF DENGUE INFECTIONS IN BANGKOK [J].
BURKE, DS ;
NISALAK, A ;
JOHNSON, DE ;
SCOTT, RM .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1988, 38 (01) :172-180
[3]   TECHNIQUES FOR HEMAGGLUTINATION AND HEMAGGLUTINATION-INHIBITION WITH ARTHROPOD-BORNE VIRUSES [J].
CLARKE, DH ;
CASALS, J .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1958, 7 (05) :561-573
[4]  
DIETZ VJ, 1990, AM J EPIDEMIOL, V131, P693
[5]  
DOHERTY R. L., 1960, AUSTRALIAN JOUR EXPTL BIOL AND MED SCI, V38, P427, DOI 10.1038/icb.1960.46
[6]  
Doherty R L, 1967, Med J Aust, V2, P1078
[7]  
GUBLER DJ, 1988, S INT FEBR AM DENG, P291
[8]   DENGUE HEMORRHAGIC-FEVER IN CUBA, 1981 - A RETROSPECTIVE SEROEPIDEMIOLOGIC STUDY [J].
GUZMAN, MG ;
KOURI, GP ;
BRAVO, J ;
SOLER, M ;
VAZQUEZ, S ;
MORIER, L .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1990, 42 (02) :179-184
[9]   DENGUE AND CHIKUNGUNYA VIRUS INFECTION IN MAN IN THAILAND, 1962-1964 .3. CLINICAL, AND VIROLOGIC OBSERVATIONS ON DISEASE IN NON-INDIGENOUS WHITE PERSONS [J].
HALSTEAD, SB ;
UDOMSAKD.S ;
SINGHARA.P ;
NISALAK, A .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1969, 18 (6P1) :984-&
[10]  
HARE, 1898, AUST MED GAZ, V17, P98