Applying Principles from Complex Systems to Studying the Efficacy of CAM Therapies

被引:17
作者
Ahn, Andrew C. [1 ,2 ]
Nahin, Richard L. [3 ]
Calabrese, Carlo [4 ]
Folkman, Susan [5 ]
Kimbrough, Elizabeth [6 ]
Shoham, Jacob [7 ]
Haramati, Aviad [8 ,9 ]
机构
[1] Harvard Univ, Sch Med, Div Res & Educ Complementary & Integrat Med Thera, Boston, MA 02215 USA
[2] Beth Israel Deaconess Med Ctr, Div Gen Med & Primary Care, Boston, MA 02215 USA
[3] NIH, Natl Ctr Complementary & Alternat Med, Bethesda, MD 20892 USA
[4] Natl Coll Nat Med, Helfgott Res Inst, Portland, OR USA
[5] Univ Calif San Francisco, Osher Ctr Integrat Med, San Francisco, CA 94143 USA
[6] Univ Maryland, Ctr Integrat Med, Baltimore, MD 21201 USA
[7] Bar Ilan Univ, Fac Life Sci, Ramat Gan, Israel
[8] Georgetown Univ, Sch Med, Dept Physiol & Biophys, Washington, DC 20007 USA
[9] Georgetown Univ, Sch Med, Dept Med, Washington, DC USA
基金
美国国家卫生研究院;
关键词
B-CELL LYMPHOMA; MORTALITY; SURVIVAL; DYNAMICS;
D O I
10.1089/acm.2009.0593
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
In October 2007, a National Center for Complementary and Alternative Medicine (NCCAM)-sponsored workshop, entitled "Applying Principles from Complex Systems to Studying the Efficacy of CAM Therapies,'' was held at Georgetown University in Washington, DC. Over a 2-day period, the workshop engaged a small group of experts from the fields of complementary and alternative medicine (CAM) research and complexity science to discuss and examine ways in which complexity science can be applied to CAM research. After didactic presentations and small-group discussions, a number of salient themes and ideas emerged. This paper article describes the workshop program and summarizes these emergent ideas, which are divided into five broad categories: (1) introduction to complexity; (2) challenges to CAM research; (3) applications of complexity science to CAM; (4) CAM as a model of complexity applied to medicine; and (5) future directions. This discusses possible benefits and challenges associated with applying complexity science to CAM research. By providing an introductory framework for this collaboration and exchange, it is hoped that this article may stimulate further inquiry into this largely unexplored area of research.
引用
收藏
页码:1015 / 1022
页数:8
相关论文
共 17 条
[1]   Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling [J].
Alizadeh, AA ;
Eisen, MB ;
Davis, RE ;
Ma, C ;
Lossos, IS ;
Rosenwald, A ;
Boldrick, JG ;
Sabet, H ;
Tran, T ;
Yu, X ;
Powell, JI ;
Yang, LM ;
Marti, GE ;
Moore, T ;
Hudson, J ;
Lu, LS ;
Lewis, DB ;
Tibshirani, R ;
Sherlock, G ;
Chan, WC ;
Greiner, TC ;
Weisenburger, DD ;
Armitage, JO ;
Warnke, R ;
Levy, R ;
Wilson, W ;
Grever, MR ;
Byrd, JC ;
Botstein, D ;
Brown, PO ;
Staudt, LM .
NATURE, 2000, 403 (6769) :503-511
[2]  
[Anonymous], NONLINEAR DYNAMICS A
[3]  
[Anonymous], 1984, QUANTITATIVE APPL SO
[4]  
[Anonymous], 2014, Introduction to Structural Equation Models
[5]   Multiscale entropy analysis of complex physiologic time series [J].
Costa, M ;
Goldberger, AL ;
Peng, CK .
PHYSICAL REVIEW LETTERS, 2002, 89 (06) :1-068102
[6]   Enabling a systems biology approach to immunology: focus on innate immunity [J].
Gardy, Jennifer L. ;
Lynn, David J. ;
Brinkman, Fiona S. L. ;
Hancock, Robert E. W. .
TRENDS IN IMMUNOLOGY, 2009, 30 (06) :249-262
[7]  
Goodwin Brian., 2001, LEOPARD CHANGED ITS
[8]  
Gorsuch GL, 1974, Factor Analysis
[9]  
Ho KKL, 1997, CIRCULATION, V96, P842
[10]   Fractal correlation properties of R-R interval dynamics and mortality in patients with depressed left ventricular function after an acute myocardial infarction [J].
Huikuri, HV ;
Mäkikallio, TH ;
Peng, CK ;
Goldberger, AL ;
Hintze, U ;
Moller, M .
CIRCULATION, 2000, 101 (01) :47-53