Photochemistry of acyloximes: synthesis of heterocycles and natural products

被引：50

作者：

Alonso, Rafael ^{[1
]}

Caballero, Alegria ^{[1
]}

Campos, Pedro J. ^{[1
]}

Rodriguez, Miguel A. ^{[1
]}

机构：

[1] Univ La Rioja, Dept Quim, Grp Sintesis Quim La Rioja, Unidad Asociada,CSIC, Logrono 26006, Spain

来源：

TETRAHEDRON | 2010年 / 66卷 / 46期

关键词：

Acyloxime; Radical; Cyclization; Heterocycles; FREE-RADICAL CYCLIZATIONS; IMINYL RADICALS; OXIMES; DIHYDROPYRROLES;

D O I：

10.1016/j.tet.2010.09.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New applications of the photochemically generated iminyl radicals ring closure onto phenyl, thiophenyl, and pyridinyl rings are presented. The influence on the reactivity of different substituent throughout the acyloxime structure is discussed. Some observed effects are interpreted from computational studies. This reaction provides a new, simple, and straightforward method for the preparation of several polycyclic heteroaromatic compounds and it has been applied to the synthesis of some natural products. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：8828 / 8831

页数：4

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