Transcription activation by a variety of AraC/XylS family activators does not depend on the class II-specific activation determinant in the N-terminal domain of the RNA polymerase alpha subunit

被引：17

作者：

Egan, SM ^{[1
]}

Pease, AJ

Lang, J

Li, X

Rao, V

Gillette, WK

Ruiz, R

Ramos, JL

Wolf, RE

机构：

[1] Univ Kansas, Dept Mol Biosci, Lawrence, KS 66045 USA

[2] Univ Maryland Baltimore Cty, Dept Biol Sci, Baltimore, MD 21250 USA

[3] NIDDKD, Mol Biol Lab, NIH, Bethesda, MD 20892 USA

[4] Dept Plant Biochem & Mol & Cellular Biol Plants, CSIC, Estac Expt Zaidin, Granada, Spain

来源：

JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 24期

关键词：

D O I：

10.1128/JB.182.24.7075-7077.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The N-terminal domain of the RNA polymerase or subunit (alpha -NTD) was tested for a role in transcription activation by a variety of AraC/XylS family members. Based on substitutions at residues 162 to 165 and an extensive genetic screen we conclude that alpha -NTD is not an activation target for these activators.

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页码：7075 / 7077

页数：3

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