Production of enterocin P, an antilisterial pediocin-like bacteriocin from Enterococcus faecium P13, in Pichia pastoris

被引：42

作者：

Gutiérrez, J ^{[1
]}

Criado, R ^{[1
]}

Martín, M ^{[1
]}

Herranz, C ^{[1
]}

Cintas, LM ^{[1
]}

Hernández, PE ^{[1
]}

机构：

[1] Univ Complutense Madrid, Fac Vet, Dept Nutr Bromatol & Tecnol Alimentos, E-28040 Madrid, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 07期

关键词：

D O I：

10.1128/AAC.49.7.3004-3008.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

The gene encoding mature enterocin P (EntP), an antimicrobial peptide from Enterococcus faccium P13, was cloned into the pPICZ alpha A expression vector to generate plasmid pJC31. This plasmid was integrated into the genome of A pastoris X-33, and EntP was heterologously secreted from the recombinant P. pastoris X-33t(1) derivative at a higher production and antagonistic activity than from E. faccium P13.

引用

页码：3004 / 3008

页数：5

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