Red Wine May be Used in the Therapy of Myocarditis

被引:5
作者
Chen, Chun-Juan [1 ]
Yu, Wei [1 ]
Wang, Wei [1 ]
机构
[1] Shantou Univ, Coll Med, Affiliated Hosp 1, Dept Cardiol, Shantou 515041, Peoples R China
关键词
INFLAMMATION; MYOCARDITIS; THERAPEUTICS; RED WINE; NF-KAPPA-B; NECROSIS-FACTOR-ALPHA; ACUTE ETHANOL TREATMENT; INFLAMMATORY BIOMARKERS; IMMUNE RESPONSIVENESS; RESVERATROL; POLYPHENOLS; ACTIVATION; EXPRESSION; AP-1;
D O I
10.1002/jcb.22882
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Myocarditis is one of the most commonly cardiovascular diseases in clinical practice, but the treatment is always limited at present. Considering the multifactorial etiology of myocarditis, a novel therapeutic agent with multi-bioactivties should be presented. Red wine has been recognized as a favorable natural medicine against a large number of pathologic conditions. Recent results indicate that red wine could effectively decrease inflammatory factors secretion, reduce the migration of neutrophils, antagonize oxidation, and regulate immunity. By these bioactivities of anti-inflammation, anti-oxidation, and immunomodulation, red wine may be an effective therapeutic candidate to manage the symptoms and prevent the recurrence of myocarditis. J. Cell. Biochem. 111: 808-810,2010. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码:808 / 810
页数:3
相关论文
共 40 条
[1]  
Arbabi S, 1999, J IMMUNOL, V162, P7441
[2]   INHIBITION OF THE PRODUCTION AND EFFECTS OF INTERLEUKIN-1 AND TUMOR-NECROSIS-FACTOR-ALPHA IN RHEUMATOID-ARTHRITIS [J].
AREND, WP ;
DAYER, JM .
ARTHRITIS AND RHEUMATISM, 1995, 38 (02) :151-160
[3]   Effects of moderate Sicilian red wine consumption on inflammatory biomarkers of atherosclerosis [J].
Avellone, G ;
Di Garbo, V ;
Campisi, D ;
De Simone, R ;
Raneli, G ;
Scaglione, R ;
Licata, G .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2006, 60 (01) :41-47
[4]   HMG-CoA reductase inhibitor attenuates experimental autoimmune myocarditis through inhibition of T cell activation [J].
Azuma, RW ;
Suzuki, J ;
Ogawa, M ;
Futamatsu, H ;
Koga, N ;
Onai, Y ;
Kosuge, H ;
Isobe, M .
CARDIOVASCULAR RESEARCH, 2004, 64 (03) :412-420
[5]   Red wine intake prevents nuclear factor-κB activation in peripheral blood mononuclear cells of healthy volunteers during postprandial lipemia [J].
Blanco-Colio, LM ;
Valderrama, M ;
Alvarez-Sala, LA ;
Bustos, C ;
Ortego, M ;
Hernández-Presa, MA ;
Cancelas, P ;
Gómez-Gerique, J ;
Millán, J ;
Egido, J .
CIRCULATION, 2000, 102 (09) :1020-1026
[6]  
Bode Ann M, 2003, Sci STKE, V2003, pRE2, DOI 10.1126/stke.2003.167.re2
[7]  
Butler DM, 1995, EUR CYTOKINE NETW, V6, P225
[8]   Reduction of oxidative stress and cytokine-induced neutrophil chemoattractant (CINC) expression by red wine polyphenols in zinc deficiency induced intestinal damage of rat [J].
Canali, R ;
Vignolini, F ;
Nobili, F ;
Mengheri, E .
FREE RADICAL BIOLOGY AND MEDICINE, 2000, 28 (11) :1661-1670
[9]  
Cooper L.T.J.R., 2009, MYOCARDITIS N ENGL J, V360, P1526
[10]  
de la Lastra CA, 2005, MOL NUTR FOOD RES, V49, P405