A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo[2,3-b]indole skeleton, a building block for 10b-hydroxy-pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4-diones

被引：53

作者：

Ley, SV ^{[1
]}

Cleator, E ^{[1
]}

Hewitt, PR ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 20期

关键词：

5-N-ACETYLARDEEMIN; OXYGENATION; DERIVATIVES; TRYPTOPHAN; AMAUROMINE;

D O I：

10.1039/b308288a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A two-step selenocyclisation-oxidative deselenation sequence was used to establish the 3a-hydroxy-pyrrolo-[2,3-b]indole core; these tricycles were used as effective precursors to 10b-hydroxy-pyrazino[1',2' : 1,5]pyrrolo-[2,3-b]indole-1,4-diones.

引用

页码：3492 / 3494

页数：3

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