Reductive C-alkylation of barbituric acid derivatives with carbonyl compounds in the presence of platinum and palladium catalysts

被引：38

作者：

Jursic, BS ^{[1
]}

Neumann, DM ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 25期

关键词：

D O I：

10.1016/S0040-4039(01)00621-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Effective synthetic procedures for the preparation of mono- and di-C-alkylated barbituric acid derivatives through palladium and platinum catalytic hydrogenation of solutions of barbituric acids (unsubstituted, N-mono, and N,N ' -disubstituted barbituric acids) and carbonyl compounds (aliphatic and aromatic aldehydes and ketones). (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4103 / 4107

页数：5

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