Kinetic resolution of racemic alpha-hydroxy ketones by lipase-catalyzed irreversible transesterification

被引：57

作者：

Adam, W ^{[1
]}

Diaz, MT ^{[1
]}

Fell, RT ^{[1
]}

SahaMoller, CR ^{[1
]}

机构：

[1] UNIV WURZBURG,INST ORGAN CHEM,D-97074 WURZBURG,GERMANY

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 08期

关键词：

D O I：

10.1016/0957-4166(96)00272-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Asymmetric acetylation of racemic a-hydroxy ketones with isopropenyl acetate catalyzed by lipases afforded the optically active keto alcohols and acetates in high enantiomeric excess (up to 99%); an enzymatic kinetic resolution which may be performed on preparative scale. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：2207 / 2210

页数：4

共 20 条

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