Ring-deactivated hydroxymethylpyrroles as inhibitors of α-chymotrypsin

被引：14

作者：

Abell, AD ^{[1
]}

Nabbs, BK ^{[1
]}

机构：

[1] Univ Canterbury, Dept Chem, Christchurch 1, New Zealand

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 2001年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0968-0896(00)00274-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

N-Acyl and N-sulfonylhydroxymetyhylpyrroles have been synthesised and shown to inhibit alpha -chymotrypsin. A hydrophobic group in the N-substituent has been shown to be required for activity. O 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：621 / 628

页数：8

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