Multiple regulatory mechanisms act on the 5′ untranslated region of the S-layer gene from Thermus thermophilus HB8

被引：13

作者：

Castán, P

de Pedro, MA

Risco, C

Vallés, C

Fernández, LA

Schwarz, H

Berenguer, J

机构：

[1] CSIC, UAM, Ctr Biol Mol Severo Ochoa, E-28049 Madrid, Spain

[2] Dept Estructura Macromol, E-28049 Madrid, Spain

[3] Dept Biotecnol Microbiana, E-28049 Madrid, Spain

[4] Ctr Nacl Biotecnol, E-28049 Madrid, Spain

[5] Max Planck Inst Entwicklungsbiol, D-72076 Tubingen, Germany

来源：

JOURNAL OF BACTERIOLOGY | 2001年 / 183卷 / 04期

关键词：

D O I：

10.1128/JB.183.4.1491-1494.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The role of the 5' untranslated region (5'UTR) of the S-layer gene from Thermus thermophilus was analyzed through the isolation of Delta5'UTR mutants. In these mutants the half-life of splA mRNA was strongly reduced and slpA transcription was no longer subjected to growth phase dependent repression. Overproduction and detachment of the external envelopes of the mutants were observed in stationary phase.

引用

页码：1491 / 1494

页数：4

共 13 条

[1]

Arnold TE, 1998, RNA, V4, P319

[2] Expression, secretion and antigenic variation of bacterial S-layer proteins [J].