Malaria transfection and transfection vectors

被引:24
作者
Gardiner, DL
Skinner-Adams, TS
Spielmann, T
Trenholme, KR
机构
[1] Univ Queensland, Malaria Biol Lab, Australian Ctr Int & Trop Hlth & Nutr, Joint Program Queensland Inst Med Res, Brisbane, Qld 4006, Australia
[2] Univ Queensland, Sch Populat Hlth, Brisbane, Qld 4006, Australia
关键词
D O I
10.1016/S1471-4922(03)00187-9
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Malaria remains a leading cause of death due to infectious disease. The completion of the Plasmodium falciparum genome sequencing project and release of preliminary proteomics data have significantly increased our understanding of the biology of this organism. Nonetheless, additional tools for functional analysis of this massive amount of information are now indispensable to further understand the basic biology of this parasite. The genetic manipulation of specific genes via the use of plasmid constructs and transfection represents one such tool.
引用
收藏
页码:381 / 383
页数:3
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