Platinum(II)/europium(III)-catalyzed intramolecular hydroalkylation of 4-pentenyl β-dicarbonyl compounds

被引：23

作者：

Liu, C ^{[1
]}

Widenhoefer, RA ^{[1
]}

机构：

[1] Duke Univ, PM Gross Chem Lab, Durham, NC 27708 USA

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/j.tetlet.2004.11.060

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of 5,5-dimethyl-8-nonene-2,4-dione with a catalytic mixture of (PtCL2(CH2=CH2)](2) (2) (1 mol%). and EuCl3, (2 mol%) in dioxane that contained HC1 (l.0equiv) at 90degreesC for 18h led to the isolation of 2-acetyl-3.6.6-trimethyl-2 -cyclohexanone in 85% yield. A number of 4-pentenyl beta-dicarbonyl compounds underwent intramolecular hydroalkylation to form Cyclohexanones in moderate to excellent yield. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：285 / 287

页数：3

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