Sequential Staudinger/Pictet-Spengler cyclization strategy for the construction of tetrahydroisoquinolines of the bioxalomycin and ecteinascidin family of alkaloids

被引：42

作者：

Herberich, B ^{[1
]}

Kinugawa, M ^{[1
]}

Vazquez, A ^{[1
]}

Williams, RM ^{[1
]}

机构：

[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 04期

关键词：

D O I：

10.1016/S0040-4039(00)02015-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of the Staudinger ketene-imine S-lactam-forming cycloaddition reaction and the Pictet-Spengler cyclization reaction in sequence, has been used to prepare highly functionalized tetrahydroisoquinolines relevant to the bioxalomycin and ecteinascidin family of antitumor alkaloids. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：543 / 546

页数：4

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