Bipolar offspring: A window into bipolar disorder evolution

被引：54

作者：

Chang, K ^{[1
]}

Steiner, H ^{[1
]}

Dienes, K ^{[1
]}

Adleman, N ^{[1
]}

Ketter, T ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Div Child & Adolescent Psychiat, Dept Psychiat & Behav Sci, Stanford, CA 94305 USA

来源：

BIOLOGICAL PSYCHIATRY | 2003年 / 53卷 / 11期

关键词：

bipolar disorder; offspring; prodromal; child; adolescent;

D O I：

10.1016/S0006-3223(03)00061-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Children of parents with bipolar disorder (bipolar offspring) represent a rich cohort for study with potential for illumination of prodromal forms of bipolar disorder. Due to their high-risk nature, bipolar offspring may present phenomenological, temperamental, and biological clues to early presentations of bipolar disorder. This article reviews the evidence for establishing bipolar offspring as a high-risk cohort, the studies which point to possible prodromal states in bipolar offspring, biological findings in bipolar offspring which may be indicators of even higher risk for bipolar disorder, initial attempts at early intervention in prodromal pediatric bipolar disorder, and implications for future research. (C) 2003 Society of Biological Psychiatry.

引用

页码：945 / 951

页数：7

共 55 条

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