Polyglycolide-based blends for drug delivery: A differential scanning calorimetry study of the melting behavior

被引:7
作者
Dickers, KJ
Huatan, H
Cameron, RE
机构
[1] Univ Cambridge, Dept Mat Sci & Met, Cambridge CB2 3QZ, England
[2] Pfizer Global R&D, Pharmaceut R&D, Sandwich CT13 9NJ, Kent, England
关键词
blends; blending; miscibility; differential scanning calorimetry (DSC);
D O I
10.1002/app.12353
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 [高分子化学与物理]; 080501 [材料物理与化学]; 081704 [应用化学];
摘要
The melting behavior of polyglycolide (PGA) with eight other biodegradable polymers was investigated to determine whether forming a blend could be used as a method of lowering the melting point of PGA. Blends were prepared by melt processing in differential scanning calorimetry (DSC) pans and were then analyzed by DSC. In every case, a comparison of the blend DSC plot with those of the two individual components showed that the melting behavior of PGA remained unchanged by blending. (C) 2003 Wiley Periodicals, Inc.
引用
收藏
页码:2937 / 2939
页数:3
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