Biochemical individuality: The next generation

被引：13

作者：

Calabrese, EJ

机构：

[1] Environmental Health Sciences Program, School of Public Health, University of Massachusetts, Amherst

来源：

REGULATORY TOXICOLOGY AND PHARMACOLOGY | 1996年 / 24卷 / 01期

关键词：

D O I：

10.1006/rtph.1996.0079

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

This paper provides an historical assessment of the development of the concepts of pharmaco- and ecogenetics, including their relationship to major developments in the areas of pharmacology, industrial hygiene, and cancer research in animal models as well as the assessment of inborn metabolic disorders. How this information may be used to evaluate the range of human genetic diversity and its relationship to differential responses to environmental toxins is also considered. The paper concludes by providing a brief summary of several specific conditions in which human genetic traits affect susceptibility to toxic substances. (C) 1996 Academic Press, Inc.

引用

页码：S58 / S67

页数：10

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