Reproduction of postweaning multisystemic wasting syndrome in pigs experimentally inoculated with a Swedish porcine circovirus 2 isolate

被引：31

作者：

Allan, G ^{[1
]}

McNeilly, F

Meehan, B

McNair, I

Ellis, J

Krakowka, S

Fossum, C

Wattrang, E

Wallgren, P

Adair, B

机构：

[1] Vet Sci Div, Dept Agr & Rural Dev, Belfast BT4 3SD, Antrim, North Ireland

[2] Queens Univ Belfast, Dept Vet Sci, Belfast BT4 3SD, Antrim, North Ireland

[3] Univ Saskatchewan, Dept Vet Med, Saskatoon, SK 57N 5B4, Canada

[4] Ohio State Univ, Coll Vet Med, Columbus, OH 43210 USA

[5] Dept Vet Microbiol, Div Immunol, SE-75189 Uppsala, Sweden

[6] Natl Vet Inst, SE-75189 Uppsala, Sweden

来源：

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION | 2003年 / 15卷 / 06期

关键词：

D O I：

10.1177/104063870301500607

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

In recent years, porcine circovirus type 2 (PCV2)-associated postweaning multisystemic wasting syndrome (PMWS) has been reported worldwide. However, to date, PMWS has not been reported in Sweden despite the demonstration of serum antibodies to a PCV2-like virus in Swedish pigs. This communication reports the experimental reproduction of clinical PMWS after inoculation of colostrum-deprived (CD) pigs, derived from a Northern Ireland herd, with an isolate of PCV2 virus recovered from a clinically normal Swedish pig that was necropsied in 1993. The clinical disease and histological lesions observed in CD pigs inoculated with this virus were indistinguishable from those observed in previous studies on CD pigs inoculated with a PCV2 virus isolate recovered from pigs with PMWS. These results highlight the disease potential of PCV2 isolated from regions apparently free of PMWS and suggest that the status of the host and its environment is an important factor in the development of clinical PMWS.

引用

页码：553 / 560

页数：8

共 18 条

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