Effect of parenteral fluoroquinolone administration on persistence of vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract

被引：29

作者：

Donskey, CJ

Helfand, MS

Pultz, NJ

Rice, LB

机构：

[1] Case Western Reserve Univ, Sch Med, Louis Stokes Cleveland DVA Med Ctr, Res Serv,Infect Dis Sect 111 W, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Sch Med, Louis Stokes Cleveland DVA Med Ctr, Med Serv, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 01期

关键词：

D O I：

10.1128/AAC.48.1.326-328.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We examined the effect of subcutaneous fluoroquinolone antibiotic administration on persistence and density of vancomycin-resistant Enterococcus faecium stool colonization in mice. Levofloxacin and ciprofloxacin did not promote colonization in comparison to saline controls, whereas moxifloxacin and gatifloxacin promoted persistent overgrowth in a dose-dependent fashion.

引用

页码：326 / 328

页数：3

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