Failure of rituximab in human immunodeficiency virus-associated multicentric Castleman disease

被引：28

作者：

Neuville, S

Agbalika, F

Rabian, C

Brière, J

Molina, JM

机构：

[1] Univ Paris, Serv Malad Infect, Hop St Louis, AP HP,Dept Infect Dis, F-75475 Paris, France

[2] Univ Paris, Dept Virol, Hop St Louis, AP HP, F-75475 Paris, France

[3] Univ Paris, Dept Immunol, Hop St Louis, AP HP, F-75475 Paris, France

[4] Univ Paris, Dept Pathol, Hop St Louis, AP HP, F-75475 Paris, France

来源：

AMERICAN JOURNAL OF HEMATOLOGY | 2005年 / 79卷 / 04期

关键词：

D O I：

10.1002/ajh.20418

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Two human immunodeficiency virus-infected patients who needed etoposide therapy to control exacerbations of Castleman disease received four infusions of rituximab. Clinical and virologic relapses with increased blood human herpesvirus-8 DNA levels occurred in both patients 4 and 24 weeks later and were associated with a worsening of Kaposi sarcoma.

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页码：337 / 339

页数：3

相关论文

共 9 条

[1] Long-term remission of Kaposi sarcoma-associated herpesvirus-related multicentric Castleman disease with anti-CD20 monoclonal antibody therapy [J].

Corbellino, M ;

Bestetti, G ;

Scalamogna, C ;

Calattini, S ;

Galazzi, M ;

Meroni, L ;

Manganaro, D ;

Fasan, M ;

Moroni, M ;

Galli, M ;

Parravicini, C .

BLOOD, 2001, 98 (12) :3473-3475

[2] Unusual viral infections (progressive multifocal leukoencephalopathy and cytomegalovirus disease) after high-dose chemotherapy with autologous blood stem cell rescue and peritransplantation rituximab [J].

Goldberg, SL ;

Pecora, AL ;

Alter, RS ;

Kroll, MS ;

Rowley, SD ;

Waintraub, SE ;

Imrit, K ;

Preti, RA .

BLOOD, 2002, 99 (04) :1486-1488

[3] Multicentric Castleman's disease: prolonged remission with anti CD-20 monoclonal antibody in an HIV-infected patient [J].

Kofteridis, DP ;

Tzagarakis, N ;

Mixaki, I ;

Maganas, E ;

Xilouri, E ;

Stathopoulos, EN ;

Eliopoulos, GD ;

Gikas, A .

AIDS, 2004, 18 (03) :585-586

[4] Rituximab therapy for HIV-associated Castleman disease [J].

Marcelin, AG ;

Aaron, L ;

Mateus, C ;

Gyan, E ;

Gorin, I ;

Viard, JP ;

Calvez, V ;

Dupin, N .

BLOOD, 2003, 102 (08) :2786-2788

[5] Prolonged remission of HIV-associated multicentric Castelman's disease with an anti-CD20 monoclonal antibody as primary therapy [J].

Marrache, F ;

Larroche, C ;

Mémain, N ;

Bouchaud, O ;

Robineau, M ;

Hermine, O ;

Lortholary, O .

AIDS, 2003, 17 (09) :1409-1410

[6] High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric Castleman disease in HIV-infected patients [J].

Oksenhendler, E ;

Carcelain, G ;

Aoki, Y ;

Boulanger, E ;

Maillard, A ;

Clauvel, JP ;

Agbalika, F .

BLOOD, 2000, 96 (06) :2069-2073

[7] Multicentric Castleman's disease in HIV infection: A clinical and pathological study of 20 patients [J].

Oksenhendler, E ;

Duarte, M ;

Soulier, J ;

Cacoub, P ;

Welker, Y ;

Cadranel, J ;

CazalsHatem, D ;

Autran, B ;

Clauvel, JP ;

Raphael, M .

AIDS, 1996, 10 (01) :61-67

[8]

Scott D, 2001, AM J HEMATOL, V66, P148

[9] KAPOSIS SARCOMA-ASSOCIATED HERPESVIRUS-LIKE DNA-SEQUENCES IN MULTICENTRIC CASTLEMANS DISEASE [J].

SOULIER, J ;

GROLLET, L ;

OKSENHENDLER, E ;

CACOUB, P ;

CAZALSHATEM, D ;

BABINET, P ;

DAGAY, MF ;

CLAUVEL, JP ;

RAPHAEL, M ;

DEGOS, L ;

SIGAUX, F .

BLOOD, 1995, 86 (04) :1276-1280