Improvement in household stoves and risk of chronic obstructive pulmonary disease in Xuanwei, China: retrospective cohort study

被引:125
作者
Chapman, RS
He, XZ
Blair, AE
Lan, Q
机构
[1] NCI, Occupat & Environm Epidemiol Branch, Div Canc Epidemiol & Genet, NIH,DHHS, Bethesda, MD 20892 USA
[2] Chulalongkorn Univ, Coll Publ Hlth, Bangkok 10330, Thailand
[3] Chinese Acad Prevent Med, Inst Environm Hlth & Engn, Beijing 100050, Peoples R China
来源
BMJ-BRITISH MEDICAL JOURNAL | 2005年 / 331卷 / 7524期
关键词
D O I
10.1136/bmj.38628.676088.55
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To test whether improvement in household coal stoves affected the incidence of chronic obstructive pulmonary disease (COPD) in Xuanwei County, China. Design Retrospective cohort study (follow-up 1976-92) comparing incidence of COPD between groups with and without chimneys. Participants 20 453 people born into homes with unvented coal stoves; 16 606 (81.2%) subsequently changed to stoves with chimneys. Intervention Installation of a chimney in households in which unvented stoves had been used previously. Results Installation of a chimney was associated with distinct reduction in the incidence of COPD. Compared with people who did not have chimneys, the Cox-modelled risk ratio (relative risk) was 0.58 (95% confidence interval 0.49 to 0.70, P < 0.001) in men and 0.75 (0.62 to 0.92, P = 0.005) in women. Modelled risk ratios were robust to different Cox model specifications. Relative risks decreased with time since stove improvement. In both sexes, the reduction in risk became unequivocal about 10 years after stove improvement. Conclusions In Xuanwei, incidence of COPD decreased markedly after household coal stoves were improved.
引用
收藏
页码:1050 / 1052A
页数:4
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