Efficacy of the Atkins diet as therapy for intractable epilepsy

被引:153
作者
Kossoff, EH [1 ]
Krauss, GL [1 ]
McGrogan, JR [1 ]
Freeman, JM [1 ]
机构
[1] Johns Hopkins Med Inst, Dept Neurol, Baltimore, MD 21205 USA
关键词
D O I
10.1212/01.WNL.0000098889.35155.72
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The ketogenic diet is effective for treating seizures in children with epilepsy. The Atkins diet can also induce a ketotic state, but has fewer protein and caloric restrictions, and has been used safely by millions of people worldwide for weight reduction. Six patients, aged 7 to 52 years, were started on the Atkins diet for the treatment of intractable focal and multifocal epilepsy. Five patients maintained moderate to large ketosis for periods of 6 weeks to 24 months; three patients had seizure reduction and were able to reduce antiepileptic medications. This provides preliminary evidence that the Atkins diet may have a role as therapy for patients with medically resistant epilepsy.
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收藏
页码:1789 / 1791
页数:3
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