Ring-opening reactions of nonactivated aziridines catalyzed by tris(pentafluorophenyl)borane

被引：94

作者：

Watson, IDG ^{[1
]}

Yudin, AK ^{[1
]}

机构：

[1] Univ Toronto, Davenport Res Labs, Dept Chem, Toronto, ON M5S 3H6, Canada

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2003年 / 68卷 / 13期

关键词：

D O I：

10.1021/jo0343578

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ring-opening reactions of nonactivated aziridines with amine nucleophiles are efficiently catalyzed by tris(pentafluorophenyl)borane leading to derivatives of trans- 1,2-diamines in high yields. A mechanistic investigation of the reaction suggests that in situ formed [(C6F5)(3)B(OH2)].H2O catalyzes the opening through a Bronsted acid manifold.

引用

页码：5160 / 5167

页数：8

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