Protein informatics towards function identification

被引：51

作者：

Kinoshita, K

Nakamura, H

机构：

[1] Yokohama City Univ, Grad Sch Integrated Sci, Turumi Ku, Yokohama, Kanagawa 2300045, Japan

[2] Japan Sci & Technol Corp, PRESTO, Struct & Funct Biomol, Kawaguchi, Saitama, Japan

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2003年 / 13卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(03)00074-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The study of structural genomics and structural proteomics has determined the tertiary structures of many hypothetical proteins, whose molecular functions could not be understood using conventional methods. In order to infer the geometrical location of the functional site, the biochemical function and the biological function of the hypothetical protein, much effort has been made in protein informatics. The importance of heterogeneous databases and various descriptors of amino acid sequences, tertiary structures and pathways on the proteome scale has been emphasised.

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页码：396 / 400

页数：5

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