DNA-based asymmetric catalysis

被引：312

作者：

Roelfes, G

Feringa, BL

机构：

[1] Univ Groningen, Dept Organ Chem, Stratingh Inst, NL-9747 AG Groningen, Netherlands

[2] Univ Groningen, Dept Biochem, NL-9747 AG Groningen, Netherlands

[3] Univ Groningen, Inst Biotechnol, NL-9747 AG Groningen, Netherlands

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 21期

关键词：

asymmetric catalysis; copper; cycloaddition; deoxyribozymes; DNA;

D O I：

10.1002/anie.200500298

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A twist in catalysis! The chirality of DNA is transferred directly to a Diels-Alder reaction by using a DNA-tethered catalyst. A catalytically active copper complex with achiral ligands self-assembles with DNA to give products with up to 90% ee, as is the case for the exo isomer of product 1. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3230 / 3232

页数：3

共 25 条

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