Cloning of a potential cytochrome P450 from the archaeon Sulfolobus solfataricus

被引：59

作者：

Wright, RL ^{[1
]}

Harris, K ^{[1
]}

Solow, B ^{[1
]}

White, RH ^{[1
]}

Kennelly, PJ ^{[1
]}

机构：

[1] VIRGINIA POLYTECH INST & STATE UNIV, DEPT BIOCHEM & ANAEROB MICROBIOL, BLACKSBURG, VA 24061 USA

来源：

FEBS LETTERS | 1996年 / 384卷 / 03期

关键词：

cytochrome P450; evolution; archaea; archaebacteria; CYP119;

D O I：

10.1016/0014-5793(96)00322-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A gene, CYP119, for a potential cytochrome P450 has been isolated and sequenced from the extreme acidothermophilic archaeon Sulfolobus solfataricus. The gene predicts a polypeptide of 368 amino adds containing the consensus heme-binding sequence Phe-Gly-Xaa-Gly-Xaa-His-Xaa-Cys-Xaa-Gly-Xaa(3)-Ala-Arg-Xaa-Glu. It most closely resembles the cytochrome P450s found in the bacterium Bacillus subtilis, with which it shares 129 identical amino acid residues (35%). This first sequence of a potential archaeal cytochrome P450 represents an important step in tracing the complex evolutionary history of this biologically important enzyme family.

引用

页码：235 / 239

页数：5

共 16 条

[1] VARIATIONS AND CODING FEATURES OF THE SEQUENCE SPANNING THE REPLICATION TERMINUS OF BACILLUS-SUBTILIS 168 AND W23-CHROMOSOMES [J].

AHN, KS ;

WAKE, RG .

GENE, 1991, 98 (01) :107-112

[2] GENE STRUCTURE, ORGANIZATION, AND EXPRESSION IN ARCHAEBACTERIA [J].

BROWN, JW ;

DANIELS, CJ ;

REEVE, JN .

CRC CRITICAL REVIEWS IN MICROBIOLOGY, 1989, 16 (04) :287-338

[3] THE FAS OPERON OF RHODOCOCCUS FASCIANS ENCODES NEW GENES REQUIRED FOR EFFICIENT FASCIATION OF HOST PLANTS [J].

CRESPI, M ;

VEREECKE, D ;

TEMMERMAN, W ;

VANMONTAGU, M ;

DESOMER, J .

JOURNAL OF BACTERIOLOGY, 1994, 176 (09) :2492-2501

[4] MOLECULAR EVOLUTION OF P450 SUPERFAMILY AND P450-CONTAINING MONOOXYGENASE SYSTEMS [J].

DEGTYARENKO, KN ;

ARCHAKOV, AI .

FEBS LETTERS, 1993, 332 (1-2) :1-8

[5] HUMAN P450PCN1 - SEQUENCE, CHROMOSOME LOCALIZATION, AND DIRECT EVIDENCE THROUGH CDNA EXPRESSION THAT P450PCN1 IS NIFEDIPINE OXIDASE [J].

GONZALEZ, FJ ;

SCHMID, BJ ;

UMENO, M ;

MCBRIDE, OW ;

HARDWICK, JP ;

MEYER, UA ;

GELBOIN, HV ;

IDLE, JR .

DNA-A JOURNAL OF MOLECULAR & CELLULAR BIOLOGY, 1988, 7 (02) :79-86

[6] CLONING AND SEQUENCE-ANALYSIS OF GENES INVOLVED IN ERYTHROMYCIN BIOSYNTHESIS IN SACCHAROPOLYSPORA-ERYTHRAEA - SEQUENCE SIMILARITIES BETWEEN ERYG AND A FAMILY OF S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES [J].

HAYDOCK, SF ;

DOWSON, JA ;

DHILLON, N ;

ROBERTS, GA ;

CORTES, J ;

LEADLAY, PF .

MOLECULAR & GENERAL GENETICS, 1991, 230 (1-2) :120-128

[7]

KIZAWA H, 1991, J BIOL CHEM, V266, P10632

[8] ISOLATION AND CLONING OF A PROTEIN-SERINE/THREONINE PHOSPHATASE FROM AN ARCHAEON [J].

LENG, J ;

CAMERON, AJM ;

BUCKEL, S ;

KENNELLY, PJ .

JOURNAL OF BACTERIOLOGY, 1995, 177 (22) :6510-6517

[9]

NEBERT DW, 1991, METHOD ENZYMOL, V206, P3

[10]

NEBERT DW, 1987, ANNU REV BIOCHEM, V56, P945, DOI 10.1146/annurev.bi.56.070187.004501

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